刚下了avastin官网的用药指南:# s, C' L+ _2 R9 A7 ?
! Y2 M5 B( J @6 P1 ? Patients should continue treatment until disease progression or unacceptable toxicity.
" Z, b: T% |7 N$ k) L" x3 m1 Metastatic Colorectal Cancer (mCRC)
: r! T$ \' c: H% m" T The recommended doses are 5 mg/kg or 10 mg/kg every 2 weeks when used in combination with / O/ g; |4 A$ N4 u7 N( j
intravenous 5-FU-based chemotherapy.
0 _% e8 J$ `* y. r4 v4 A! r- l3 B• Administer 5 mg/kg when used in combination with bolus-IFL. , A s6 a+ z: \9 b4 Y+ n0 d1 N
• Administer 10 mg/kg when used in combination with FOLFOX4. : C$ P3 s1 D6 |* ^4 o4 k
2 Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
* F( D' Z; i: [$ t- Z6 s- ? The recommended dose is 15 mg/kg every 3 weeks in combination with carboplatin and - K- ?! j+ a b- `: l' c+ n
paclitaxel.
3 C( @3 i4 J: F" k3 Metastatic Breast Cancer (MBC) : l% H5 X/ f& q0 z
The recommended dose is 10 mg/kg every 2 weeks in combination with paclitaxel.
8 ^6 r9 w- }9 J" x" ?% K4 Glioblastoma
1 s+ T! W0 x4 k4 D9 Z# ], ^) d The recommended dose is 10 mg/kg every 2 weeks.
- z# o0 a5 }/ o2 o+ F5 Metastatic Renal Cell Carcinoma (mRCC)
: o0 J: F. `; ] The recommended dose is 10 mg/kg every 2 weeks in combination with interferon alfa. ! I. W: L) c: c! ^# v1 w
- F' t- X' _5 d
按照这个说明非小细胞腺癌的服用剂量是15mg/kg,与卡铂紫杉醇合用,avastin每三周用一次。) c* j# Q3 D9 x8 L
我妈妈是肺腺癌转肝,体重53kg,现在医生联合卡铂紫杉醇化疗了一个疗程21天。 但avastin不是一次注射的,每7天注射一次200mg,一个疗程21天注射了3次(分别是第一、八、十五天) |